According to Tooele County Sheriffs Department dispatch the crash happened at about 5:30pm near mile marker 88 on I-80.
Tooele officials said the female driver traveled approximately four miles east in the westbound lane before hitting the left rear trailer tire of a semi truck, which pushed her vehicle into the middle of the highway.
After this crash, another semi swerving to miss her vehicle collided with her head on.
The driver of the passenger vehicle suffered a broken leg, but no other injuries were reported.
Authorities say she was taken to the hospital in a life flight helicopter as a precaution.
Officials are also reporting they believe the female driver of the passenger car has a medical condition that may have contributed to the accident.