SMU took the lead for good by scoring the last 11 points before halftime. The Mustangs made its first six 3-pointers of the game, including three in a first half, ending a 17-3 run that included those last 11 points.
Utah (4-2) appeared to have a tying 3-pointer midway through the second half, but during a timeout 10 seconds after that shot, officials looked at replays and ruled that Jarred DuBois' foot was on the line, making it two points instead.
The Mustangs are 4-0 at Moody Coliseum under Brown, the Hall of Fame coach who in the college ranks at Kansas, UCLA and now SMU, is 99-11 in home games.
The Utes next play at Texas State Friday night.